Tetrapocillon is a genus of sponges belonging to the family Guitarridae.

The genus was first described in 1924 by Holger Valdemar Brøndsted,Brøndsted, H. V. (1924). Papers from Dr. Th. Mortensen’s Pacific Expedition 1914-16. XXIII. Sponges from New Zealand. Part I. Videnskabelige Meddelelser Fra Dansk Naturhistorisk Forening I Kjøbenhavn, 77: 435–483 . with the type species being Tetrapocillon novaezealandia.

Species Species accepted by WoRMS are: Tetrapocillon atlanticus Tetrapocillon kurushimensis Tetrapocillon minor Tetrapocillon novaezealandiae Tetrapocillon patbergquistae

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