Empress Margaret may refer to:

Margaret of Hungary (Byzantine empress) (1175–?), wife of Isaac II Angelos Margaret II, Countess of Hainaut (1311–1356), wife of Louis IV, Holy Roman Emperor Margaret Theresa of Spain (1651–1673), wife of Leopold I, Holy Roman Emperor

See also Margaret of Brabant (1276–1311), wife of Henry of Luxembourg, King of Germany, later Holy Roman Emperor (after her death) Queen Margaret (disambiguation)