Chisala is a Bantu surname. Notable people with the name include:
Surname Obino Chisala (born 1999), Zambian footballer Philemon Chisala (born 1966), Zambian footballer Sarai Chisala-Tempelhoff (born 1980s), Malawian lawyer and activist Upile Chisala (born 1994), Malawian poet Wilson Chisala Kalumba (1964–2018), Zambian politician