Pacino is a given name and a surname. Notable people with the name include:

Given name Pacino di Buonaguida (active 1303 – 1347), Italian painter Pacino Horne (born 1983), American football player

Surname Al Pacino (born 1940), American actor Evelyn Sanguinetti (née Pacino; born 1970), American politician, lawyer and lieutenant governor of Illinois (2015–2019) Julie Pacino (born 1989), American filmmaker, daughter of Al Pacino Katherin Kovin Pacino (1952–2024), American actress and child advocate