Spinazzola is an Italian surname from Barletta–Andria–Trani, derived from the local town of Spinazzola.

Alda Levi Spinazzola (; 1890–1950), Italian archaeologist and art historian Leonardo Spinazzola (born 1993), Italian footballer

See also

Pope Innocent XII (1615–1700), born Antonio Pignatelli, son of the Marquess of Spinazzola