O'Malley may refer to:

O'Malley (surname), a surname (including a list of people with the name) O'Malley, Australian Capital Territory, a suburb of Canberra , a research vessel in commission in the United States Fish and Wildlife Service from 1949 to 1951 Ó Máille clan or Kings of Umaill, an Irish clan name anglicized as O'Malley

See also Malley Maley Mally (disambiguation) Maly (disambiguation)