3,4,5-Trimethoxyphenoxyethylamine is a chemical compound of the phenoxyethylamine family related to the psychedelic phenethylamine mescaline. "One additional manipulation with some of these [mescaline-related] structures has been made and should be mentioned. These are the analogues with an oxygen atom inserted between the aromatic ring and the aliphatic chain. They are, in essence, aminoethyl phenyl ethers. The first is related to mescaline itself, 2-(3,4,5-trimethoxyphenoxy)ethylamine. Human trials were conducted over the dose range of 10 to 300 milligrams and there were no effects observed. The second is related to trichocerine, N,N-dimethyl-2-(3,4,5-trimethoxyphenoxy)ethylamine. It was inactive in man over the range of 10 to 400 milligrams. Mescaline, at a dose of 420 milligrams, served as the control in these studies." It is the analogue of mescaline in which an oxygen atom has been inserted between the benzene ring and the ethylamine side chain. The drug was tested in humans at doses of 10 to 300mg orally but was found to be inactive. For comparison, mescaline is active at doses as low as 100mg orally. 3,4,5-Trimethoxyphenoxyethylamine was first described and studied by A. Carlsson and colleagues in 1963. It was subsequently reviewed by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved) and other publications.
See also Phenoxyethylamine CT-4719 CT-5126 ORG-37684
References
External links 2-(3,4,5-Trimethoxyphenoxy)ethylamine - Isomer Design