Killingholme may refer to:
North Killingholme, village and civil parish in Lincolnshire, England Historical references (pre 20th century), to "Killingholme" generally imply North Killingholme the larger of the two villages North Killingholme Haven, a harbour in Lincolnshire South Killingholme, village and civil parish in Lincolnshire, England RNAS Killingholme, a First World War seaplane base RAF North Killingholme, an airfield, used extensively during the Second World War Killingholme railway station, Lincolnshire, England , a paddle steamer