James Grayson may refer to: People James Grayson (music industry executive) (1897–1980), English music industry executive James Grayson (rugby union player) (born 1998), English professional rugby union player James H. Grayson (born 1944), American scholar of religions and folklore of Korea James Grayson, bass player in the band Trash Boat James Grayson, a Tennessee politician referenced in the song "Tom Dooley"
Fictional characters James Grayson, two characters in the 1916 film The Race James Grayson, a character in the 1935 film The Pecos Kid James Grayson, a character in the video game series Resistance