Mwanamwambwa is a surname. Notable people with the surname include:

Amusaa Mwanamwambwa (1940–2023), Zambian politician Marvin Sitwala Mwanamwambwa (born 1954) Retired Deputy Chief Justice of the Republic of Zambia and current Judge President of the COMESA Court of Justice Ngozi Mwanamwambwa (born 1971), Zambian sprinter