Coene and De Coene are surnames. Notable people with the names include:

Coene Constantinus Fidelio Coene (1779–1841), painter of history, genre, and landscape pieces Dominique Coene (born 1982), Belgian former professional tennis player Eline Coene (born 1964), Dutch badminton player Jacques Coene (1380–1411), Flemish painter, illustrator and architect Jan Coene (born 1957), Belgian businessman, disgraced by the Picanol Scandal Luc Coene (1947–2017), Belgian economist

De Coene Jean Henri De Coene (1798–1866), Belgian painter of genre and historical subjects