Helaine is a given name. Notable people with the name include:
Helaine M. Barnett, American legal aid attorney and law professor Helaine Blumenfeld (born 1942), American sculptor, especially of large-scale public sculptures Candace Helaine Cameron Bure (born 1976), American actress and former talk show panelist Helaine Fendelman (born 1942), antiques, fine arts and collectibles appraiser and author Helaine Greenfeld (born 1963), American attorney Helaine Head (born 1947), American film, television, and theatre director Helaine Newstead (1906–1981), American scholar of medieval literature Helaine Olen, American journalist and author Helaine Selin (born 1946), American librarian, historian of science, author, book editor