Koomson is a surname. Notable people with the surname include:
Dorothy Koomson (born 1971), British novelist George Kingsley Koomson, Ghanaian judge Gilbert Koomson (born 1994), Ghanaian footballer Koby Arthur Koomson, Ghanaian diplomat Mavis Hawa Koomson (born 1966), Ghanaian politician Valencia Koomson, American electrical engineer