NGC5374 is a barred spiral galaxy in the constellation of Virgo. Its velocity with respect to the cosmic microwave background is , which corresponds to a Hubble distance of . Additionally, seven non-redshift measurements give a similar mean distance of . It was discovered by German-British astronomer William Herschel on 12 May 1793.

NGC 5374 is a radio galaxy, i.e. it has giant regions of radio emission extending well beyond its visible structure.

NGC 5374 group According to A. M. Garcia, NGC 5374 is the namesake of a group of galaxies. The NGC 5374 group (also known as LGG 368) contains at least eight galaxies, including , NGC 5384, , , , , and .

Supernovae Three supernovae have been observed in NGC 5374: SN2003bl (TypeII, mag. 18.4) was discovered by LOTOSS (Lick Observatory and Tenagra Observatory Supernova Searches) on 2 March 2003. SN2010do (TypeIc, mag. 17.2) was discovered by on 2 June 2010. SN2016P (Type Ic-BL, mag. 16) was discovered by Grzegorz Duszanowicz and Michal Zolnowski on 19 January 2016.

See also List of NGC objects (5001–6000)

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