Bárcena is a Spanish surname. Notable people with the surname include:
Alicia Bárcena (born 1952), Mexican biologist and the United Nations Executive Secretary of ECLAC Alonzo de Barcena (1528–1598), Spanish Jesuit missionary and linguist Catalina Bárcena (1888–1978), Spanish theatre actress David Bárcena Ríos (1941–2017), Mexican equestrian Juan Gómez Bárcena (born 1984), Spanish author and literary critic Marisol Vargas Bárcena (born 1975), Mexican politician Martha Bárcena Coqui (born 1957), Mexican diplomat Rafael García Bárcena (1907–1961), Cuban philosopher
See also De la Bárcena