Centpyraquin, also known as IHCH-7162 or as compound 69-183, is a serotonin receptor modulator related to the partial ergolines and phenylpiperazines. It is a serotonin 5-HT1A receptor agonist and a mixed modulator of the serotonin 5-HT2A receptor, acting as a weak partial agonist of G protein signaling and as an antagonist of β-arrestin2 recruitment. The drug has antipsychotic-like, CNS depressant, and antihypertensive effects in animals. Centpyraquin was developed by researchers in India and first described by the 1970s before being studied and described further in 2024.
See also IHCH-7179 Centpropazine
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