Wyche is a surname, and may refer to: C. Thomas Wyche (1926–2015), American lawyer and conservationist Charles Cecil Wyche (1885–1966), judge Cyril Wyche (1632–1707), president of the Royal Society Cyril Wyche (Wyche baronets) (1695–1756), 1st Baronet, Ambassador to Russia Ira T. Wyche (1887–1981), American major general James Wyche (born 1982), American football player Jane Wyche (17th century), wife of John Granville, 1st Earl of Bath Larry D. Wyche, retired U.S. Army Lieutenant General Nathaniel Wyche (1607–1659), president of the English East India Company Peter Wyche (ambassador) (1593–1643), English Ambassador to the Ottoman Empire Peter Wyche (diplomat) (1628–1699), English Ambassador to Russia and Poland Richard Wyche Richard of Chichester (1197–1253), Saint and Bishop of Chichester Richard Wyche (merchant) (1554–1621), director of the English East India Company Sam Wyche (1945–2020), former American football coach and player Sid Wyche (1922–1983), American songwriter Steve Wyche (born 1966), American football journalist and broadcaster Zelma Wyche (1918–1999), Louisiana politician and African-American civil rights activist Rachel Wyche (2003), Feminist, environmentalist and writer
See also Wyche Fowler, former U.S. Senator and Ambassador Wyche, Virginia, community in Brunswick County, U.S. Wyche, Worcestershire, suburb of Malvern, England Wyche Island, Antarctica Dark Eldar, elements of a work of fiction: wych cult Droitwich, England, settlement for which Wyche was an old name