Shirley is a surname, and may refer to:
A Aaron Shirley (1933–2014), American physician and civil rights activist Alan Shirley (1937–2004), American politician Aleda Shirley (1955–2008), American poet Alex Shirley (1921–1990), Scottish footballer Alexander O. Shirley (1927–2016), British Virgin Islands cricketer, civil servant and activist Ann Savours Shirley (1927–2022) was a British historian of polar exploration, Anne Shirley (actress) (1918–1993), American actress Anthony Shirley (1565–c.1635), English adventurer and diplomat Sir Anthony Shirley, 1st Baronet (1624–1683), English politician Arthur Shirley (1886–1967), Australian actor, writer and director
B Bart Shirley (1940–2025), American baseball player Bill Shirley (1921–1989), American actor, singer and theatre producer Bob Shirley (born 1954), American baseball player
C Caroline Shirley, Duchess Sforza Cesarini (1818–1897), Englishwoman who married into the Italian aristocracy Cliff Shirley (1917–2001), New Zealand cricketer Craig Shirley (born 1956), American author and consultant
D Daniel Shirley (born 1979), New Zealand badminton player Danny Shirley (born 1956), American country music singer and songwriter David A. Shirley (1934–2021), American chemist Dallas Shirley (1913–1994), American basketball referee Don Shirley (1927–2013), American-Jamaican pianist and composer Donal Shirley (born 2005), Irish hurler Donna Shirley (born 1941), American aerospace engineer and NASA manager Dorinea Shirley (1899–1973), British film actress of the silent era Dorothy Shirley (born 1939), British athlete
E Edwin Shirley (1948–2013), British rock concert tour organiser, impresario and film studio manager Elizabeth Shirley (1564–1641), English Augustinian nun and author Eric Shirley (born 1929), British steeplechase athlete Evelyn Shirley (1788–1856), British politician Evelyn Shirley (1812–1882), British politician, antiquarian and genealogist
F Florence Shirley (1892–1967), American stage and film actress Francis Shirley (c.1524–1578), English politician Fred Shirley (1890–1967), Anglican priest and headmaster
G George Shirley (born 1934), American operatic tenor Sir George Shirley, 1st Baronet (1559–1622), English landowner Gordon Shirley (born 1956), Jamaican academic and diplomat Graham Shirley, Australian author and filmmaker
H Henry Shirley (dramatist) (died 1627), English dramatist Hardy L. Shirley (died 1996), American forester, author and academic Henry G. Shirley (1874–1941), American engineer, Commissioner of Highways in Virginia Henry Shirley, 3rd Earl Ferrers (1691–1745), English peer Sir Henry Shirley, 2nd Baronet (1589–1633), English landowner and local politician Horatio Shirley (1805–1879), British general Hubert Shirley-Smith (1901–1981), British civil engineer Hunter B. Shirley (1927–2010), American clinical psychologist
I Ian Shirley (1940–2019), New Zealand public policy academic
J Jack Shirley, American record producer, audio engineer and musician James Shirley (1596–1666), English dramatist Jason Shirley (born 1985), American football player Jerry Shirley (born 1952), English rock drummer Jill Parker-Hammersley-Shirley (born 1951), English table tennis player Jimmy Shirley (1913–1989), American jazz and R&B guitarist Joe Shirley Jr. (born 1947), Navajo politician John Shirley (born 1953), American author of genre fiction, non-fiction and lyrics John Shirley (scribe) (c. 1366–1456), English author and translator John Shirley (footballer) (1902–1968), English footballer John Shirley (sailor) (born 1958), British Virgin Islands competitive sailor John K. Shirley (1898–1954), Australian architect John Shirley-Quirk (1931–2014), English bass-baritone Jon Shirley (born 1938), American Microsoft Corporation executive Josh Shirley (born 1992), American football player
K Kellie Shirley (born 1981), English actress Ken Shirley (born 1950), New Zealand politician Kevin Shirley (born 1960), South African music producer
L Laurence Shirley, 4th Earl Ferrers (1720–1760), English peer hanged for murder Lemuel B. Shirley (1916–1999), Episcopal bishop of Panama Lianne Shirley (born 1975), New Zealand badminton player
M Mack Shirley (born 1933), American politician from Idaho Marion Shirley (1922–1996), American football player Marlon Shirley (born 1978), American paralympic athlete Mary Shirley, Countess Ferrers (bapt.1733–1807), English noblewoman Mercedes Shirley (1926–1999), American actress Mule Shirley (1901–1955), American baseball player
N Natalie Shirley (born 1957), American lawyer, businesswoman and university president Nathan Shirley, state legislator in Mississippi Nick Shirley (born 2002), American YouTuber Norma Shirley (1938–2010), Jamaican chef
P Paul Shirley (born 1977), American basketball player and writer Paul Shirley (politician), American politician from California Peter Shirley (born 1963), American computer scientist and computer graphics researcher Philip Shirley (1913–1998), British businessman
R Raphaele Shirley (born 1969), French-American multimedia artist Ray Shirley, American actress Rhys Shirley (born 2003), English footballer Robert Shirley (1581–1628), English traveller and adventurer Robert Shirley (FRS) (1673–1699), English politician and aesthete Robert Shirley (MP) (1700–1738), British politician Robert Shirley (footballer) (born 1980), Australian rules footballer Robert Shirley, 1st Earl Ferrers (1650–1717), English peer and courtier Robert Shirley, 6th Earl Ferrers (1723–1787), British peer Robert Shirley, 7th Earl Ferrers (1756–1827), British peer Robert Shirley, 12th Earl Ferrers (1894–1954), British politician Robert Shirley, 13th Earl Ferrers (1929–2012), British politician Robert Shirley, Viscount Tamworth (1692–1714), English politician Sir Robert Shirley, 4th Baronet (1629–1656), English royalist conspirator Roy Shirley (1944–2008), Jamaican singer
S Samantha Shirley (born 1983), Canadian ice hockey player Sewallis Shirley (1709–1765), British Member of Parliament Sewallis Shirley (MP) (1844–1904), British politician and founder of The Kennel Club Sewallis Shirley, 10th Earl Ferrers (1847–1912), British peer Simon Shirley (born 1966), Australian decathlete Sophie Shirley (born 1999), Canadian ice hockey player Steve Shirley (1933–2025), British information technology pioneer, businesswoman and philanthropist Steve Shirley (baseball) (born 1956), American baseball pitcher
T Tanya Shirley (born 1976), Jamaican poet Tex Shirley (1918–1993), American baseball pitcher Thomas Shirley (died 1544), English politician Thomas Shirley (c.1564–c.1634), English soldier, adventurer and politician Thomas Shirley (RAF officer) (1908–1982), British Royal Air Force officer Thomas Shirley (died 1612) (c.1542–1612), English Member of Parliament, government official and courtier Sir Thomas Shirley, 1st Baronet (1727–1800), British military officer and colonial governor
W Walter Shirley (MP) (died 1425), member of the Parliament of England Walter Shirley (priest and controversialist) (1725–1786), English Anglican cleric, hymnwriter and controversialist Walter Shirley (bishop) (1797–1847), English Anglican bishop Walter Shirley Shirley (1851–1888), English barrister, legal writer and politician Walter Shirley, 11th Earl Ferrers (1864–1937), British architect and peer Washington Shirley, 5th Earl Ferrers (1722–1778), British Royal Navy officer Washington Shirley, 8th Earl Ferrers (1760–1842), British peer Washington Shirley, 9th Earl Ferrers (1822–1859), British peer William Shirley (1694–1771), British colonial governor of Massachusetts William Shirley (cricketer) (1900–1970), English colonial police officer in British Nigeria and cricketer William Thomas Shirley (1876–1929), British-Australian WWI veteran