Cain is a masculine given name. It is borne by:

Cain, the son of Adam and Eve in the Bible Cain Ackland (born 1982), former Australian rules footballer Cain Attard (born 1994), Maltese footballer Cain Cressall, Australian singer and vocal coach Cain Culto, American singer and violinist Cain Dotson (born 1971), Swedish former footballer Cain Fara (born 1994), Argentine footballer Cain Hope Felder (1943–2019), American biblical scholar and professor Cain Liddle (born 1975), former Australian rules footballer Cain Madden (born 1996), American football player Cain Mathema (born 1947), Zimbabwean politician and writer Cain Robb (born 2003), English rugby league footballer Cain Sandoval (born 2002), American boxer Cain Sartain (1843–1902), American planter, justice of the peace, sheriff, and state legislator Cain Seedorf (born 2000), Dutch footballer Cain Velasquez (born 1982), Mexican-American mixed martial arts fighter and 2010 UFC heavyweight champion