2,3,5,6-Tetramethoxyphenethylamine (2,3,5,6-TeMPEA), also known as TeMPEA-3, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the possible positional isomers of tetramethoxyphenethylamine (TeMPEA).
The in-vitro metabolism and effects of TeMPEA-3 on behavior in animals have been studied. Unlike mescaline, TeMPEA-3 was inactive in the conditioned avoidance response test in rats. The effects of TeMPEA-3 in humans have not been reported and are unknown.
The drug was first described in the scientific literature by 1955. TeMPEA-3 was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. It is a controlled substance in Canada under phenethylamine blanket-ban language.
See also Substituted methoxyphenethylamine Tetramethoxyphenethylamine (TeMPEA) 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA, TeMPEA-1) 2,3,4,6-Tetramethoxyphenethylamine (TeMPEA-2) 2,3,5,6-Tetramethoxyamphetamine (TeMA-3) Pentamethoxyphenethylamine (PeMPEA) Trimethoxyphenethylamine (TMPEA)
References
External links TeMPEA-3 - Isomer Design