The 2005 Delaware State Hornets football team represented Delaware State University as a member of the Mid-Eastern Athletic Conference (MEAC) in the 2005 NCAA Division I-AA football season. The Hornets were led by second-year head coach Al Lavan and played their home games at Alumni Stadium. They finished the season 7–4 overall and 6–2 in conference play to place in third in the MEAC.

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