Many synthetic cannabinoids were designed by Stargate International, a now defunct New Zealand company in the 2000s and 2010s, and feature an alphanumeric code beginning with the prefix "SGT". PB-22 (SGT-21) is credited with being the first synthetic cannabinoid to feature a quinoline substructure with an ester linker at the indole 3-position. The mainly N-cumyl-indazole-3-carboxamide derivatives are best known. Many SGT compounds are banned as designer drugs in various jurisdictions, such as Japan.Pharmaceutical and Medical Device Act (previously the Pharmaceutical Affairs Act) Designated Substance. 16 May 2025

Chemical structures of SGT cannabinoid compounds Structure Name Chemical name CAS # PubChem SGT-4 (CHM-081) [1-(cyclohexylmethyl)indol-3-yl]-(4-methoxynaphthalen-1-yl)methanone 1373876–34–6 118796420 SGT-13 (2F-QMPSB) 8-quinolinyl 4-methyl-3-[(4,4-difluoropiperidin-1-yl)sulfonyl]benzoate 2707165–48–6 155884739 SGT-14 (EAM-2201) (4-Ethyl-1-naphthalenyl)[1-(5-fluoropentyl)-1H-indol-3-yl]-methanone 1364933–60–7 71308187 SGT-17 (THJ-018) 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone 1364933–55–0 124518671 SGT-20 (5F-JWH-398) (4-Chloronaphthalen-1-yl)-[1-(5-fluoropentyl)indol-3-yl]methanone 1391486–12–6 125181332 SGT-21 (PB-22, QUPIC) 1-Pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester 1400742–17–7 71604304 SGT-24 (CUMYL-PINACA) 1-pentyl-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 1400742–15–5 86273676 SGT-25 (5F-CUMYL-PINACA) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 1400742–16–6 86274158 SGT-32 (BB-22, QUCHIC) 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester 1400742–42–8 71711120 SGT-37 (A-CHMINACA) N-(1-adamantyl)-1-(cyclohexylmethyl)indazole-3-carboxamide 1400742–33–7 137700313 SGT-40 (Adamantyl-THPINACA isomer 1) N-(1-Adamantyl)-1-(tetrahydropyran-4-ylmethyl)indazole-3-carboxamide 1400742–48–4 129532625 SGT-42 (CUMYL-THPINACA) 1-(oxan-4-ylmethyl)-N-(2-phenylpropan-2-yl)indazole-3-carboxamide 1400742–50–8 86273679 SGT-48 (PTI-1) N,N-diethyl-N-((2-(1-pentyl-1H-indol-3-yl)thiazol-4-yl)methyl)ethanamine 1400742–46–2 124037378 SGT-49 (PTI-2) N-(2-methoxyethyl)-N-((2-(1-pentyl-1H-indol-3-yl)thiazol-4-yl)methyl)propan-2-amine 1400742–45–1 124037377 SGT-55 (CUMYL-BICA) 1-butyl-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide 1400742–22–4 86273677 SGT-56 (CUMYL-PICA) 1-pentyl-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide 1400742–32–6 86273678 SGT-64 (4'F-CUMYL-5F-PICA) 1-(5-fluoropentyl)-N-[2-(4-fluorophenyl)propan-2-yl]indole-3-carboxamide 1631074–52–6 117650357 SGT-65 (4'F-CUMYL-5F-PINACA) 1-(5-fluoropentyl)-N-[2-(4-fluorophenyl)propan-2-yl]indazole-3-carboxamide 1631074–53–7 117650358 SGT-78 (CUMYL-4CN-BINACA) 1-(4-Cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 1631074–54–8 117650402 SGT-88 (THQ-PINACA) 3,4-dihydro-2H-quinolin-1-yl-(1-pentylindazol-3-yl)methanone 2950480–11–0 165361626 SGT-149 (CUMYL-FUBINACA) 1-[(4-fluorophenyl)methyl]-N-(2-phenylpropan-2-yl)indazole-3-carboxamide 1631074–58–2 117650352 SGT-151 (CUMYL-PEGACLONE) 2,5-Dihydro-2-(1-methyl-1-phenylethyl)-5-pentyl-1H-pyrido[4,3-b]indol-1-one 2160555–55–3 134818034 SGT-152 (CUMYL-NBMINACA) [1-(bicyclo[2.2.1]heptan-2-yl)methyl]-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 1631074–60–6 117650372 SGT-157 (4'Cl-CUMYL-PINACA) N-[2-(4-chlorophenyl)propan-2-yl]-1-pentylindazole-3-carboxamide 1631074–65–1 86274160 SGT-194 (Adamantyl-THPINACA isomer 2) N-(2-Adamantyl)-1-(tetrahydropyran-4-ylmethyl)indazole-3-carboxamide 2365471–86–7 123132009 SGT-263 (5F-CUMYL-P7AICA) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)pyrrolo[2,3-b]pyridine-3-carboxamide 2171492–36–5 129532613 SGT-270 (CUMYL-CH-MEGACLONE) 2,5-Dihydro-2-(1-methyl-1-phenylethyl)-5-(cyclohexylmethyl)-1H-pyrido[4,3-b]indol-1-one 2813950–07–9 155884822 SGT-271 (CUMYL-BC-HPMEGACLONE) 5-({Bicyclo[2.2.1]heptan-2-yl}methyl)-2-(2-phenylpropan-2-yl)-1H,2H,5H-pyrido[4,3-b]indol-1-one 163190698 SGT-273 (CUMYL-CBMEGACLONE) 2,5-Dihydro-2-(1-methyl-1-phenylethyl)-5-(cyclobutylmethyl)-1H-pyrido[4,3-b]indol-1-one 2806439–13–2 155884737 SGT-277 (CUMYL-CBMINACA) 1-(cyclobutylmethyl)-N-(2-phenylpropan-2-yl)indazole-3-carboxamide 3001262–62–7 155884799 SGT-280 (CUMYL-CBMICA) 1-(cyclobutylmethyl)-N-(2-phenylpropan-2-yl)indole-3-carboxamide 2571070–88–5 155884426

See also List of AM cannabinoids List of CP cannabinoids List of HU cannabinoids List of JWH cannabinoids List of miscellaneous designer cannabinoids

External links Cannabinoid collection, isomerdesign.com

References