BIBN 99 is an antagonist of mACh receptors. Specifically, it is selective for the M2 type, and was prototypical for this class of selective compounds. BIBN 99 is lipophilic, it crosses the blood-brain barrier and is a competitive antagonist of the M2 receptor with 30-fold selectivity over M1 receptors.
Effects During research, it was observed that BIBN 99 was able to diminish the cognitive deficits caused by injury. Another also came to the conclusion that the compound could provide cognitive improvements. The cognitive effects could possibly be caused by the increased release of acetylcholine, a neurotransmitter.
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