Orbegozo is a Spanish surname. Notable people with the surname include:
(1921–2006), Peruvian politician (born 1979), Spanish lawyer and politician (1923–1998), Peruvian doctor and Catholic bishop José Luis Orbegozo (1929–2010), Spanish businessman and sports leader (1856–?), Spanish doctor who was the first director of the Reina Victoria Asylum (1837–1891), Spanish poet Mikel Orbegozo (born 1989), Spanish footballer (born 1959), Spanish former footballer