Diphenylacetic acid is an organic chemical with applications in drug synthesis. Applications AB06-117 (cmp #23) Adiphenine Arpenal Asimadoline 2,2-DEP [36794-51-1] Desmethylmoramide [957-51-7] Herbicide Dioxaphetyl butyrate Fluperamide Loperamide PD-85639 Moramide Pifenate Tropacine BIBO-3304 [191868-13-0] BIBP-3226 PC4225440 4-Tert-butyl-1-(2,2-diphenylethyl)-4-piperidinol (Butaclamol analog)
Synthesis From hydroiodic acid reduction of benzilic acid.
Alternative procedure:
From chloral and benzene:Kesslin, George, (1952 to Kay-Fries Chemicals Inc).Herbert R Elkinton, Kesslin George, & Nicholl Leonard, (1950 to Kay-Fries Chemicals Inc).
From glyoxylic acid and benzene: See also Diphenylacetonitrile References