Bertoletti is a surname. Notable people with the surname include:
Antoine Marc Augustin Bertoletti (1775–1846), Italian army officer Maria Bertoletti Toldini (1656–1716), Italian farmeress Patrick Bertoletti (born 1985), American competitive eater Paulo Bertoletti, Brazilian professional footballer Simone Bertoletti (born 1974), former Italian cyclist
See also Bartoletti Bortoletti