Cler is a Spanish surname. Notable people with the surname include:
Barthélemy de Cler (c. 1420 – c. 1470), an Early Netherlandish artist who worked in France as a painter and manuscript illuminator Damien Cler (born 1983), French rugby forward Louis Cler (1905–1950), French footballer Tim de Cler (born 1978), Dutch former professional footballer