Winstead is an American surname. Notable people with the surname include:
Charles Winstead (1891–1973), one of the three FBI agents who shot and killed John Dillinger Isaiah Winstead (born 1999), American football player Lizz Winstead (born 1961), American comedian, radio and television personality, and blogger Mary Elizabeth Winstead (born 1984), American actress Nash Winstead (1925–2008), North Carolina State University assistant professor and administrator in various positions W. Arthur Winstead (1904–1995), U.S. Representative from Mississippi Wendy Winstead (?–1990), American veterinarian and author Doodles Weaver (1911–1983), born Winstead Sheffield Weaver, American actor and comedian