Cloutier is a French occupational name for a nailer, from an agent derivative of clou (Latin clavus) for "nail". Most people with the surname Cloutier are descendants of Zacharie Cloutier, a pioneer who settled in New France from Perche, France in 1634 and founded one of the foremost families of Quebec. Notable people with the name include:

Albert Edward Cloutier (1902–1965), Canadian painter Alexandre Cloutier (born 1977), Canadian politician Armand Cloutier (1901–1982), Canadian politician Braeden Cloutier (born 1974), American soccer coach and player Carl-Antoni Cloutier (born 1996), Canadian professional gamer better known as CarlJr. Catherine Cloutier (born 1950), American politician Cécile Cloutier (1930–2017), Canadian writer and educator Claude Cloutier (born 1957), Canadian film animator and graphic novel artist Dan Cloutier (born 1976), Canadian ice hockey player Dave Cloutier (1938–2017), American football player Émile Proulx-Cloutier (born 1983), Canadian actor and musician Fabien Cloutier (born 1975), Canadian actor and playwright François-Xavier Cloutier (1848–1934), Canadian cleric and Bishop of Trois Rivières Frederic Cloutier (born 1981), Italian ice hockey player Gary Cloutier (born 1962), American politician George Cloutier (1876–1946), Canadian lacrosse player Gilles Cloutier (1928–2014), Canadian scientist Guy Cloutier (born 1940), Canadian music producer and convicted sex offender Guylaine Cloutier (born 1969), Canadian international swimmer Jacques Cloutier (born 1960), Canadian ice hockey player James Cloutier (born c. 1938), American cartoonist Jean Cloutier (born c. 1959), Canadian politician Jean-Paul Cloutier (1924–2010), Canadian politician John Cloutier (born 1957), American politician Julie Cloutier (born 1986), Canadian fencer Kim Cloutier (born 1987), Canadian model Kristen Cloutier, American politician Loïc Cloutier (born 2004), Canadian soccer player Milaine Cloutier (born 1972), Canadian badminton player Nathalie Cloutier, Canadian film producer Patrick Cloutier (born 1970), Canadian soldier who became famous during the 1990 Oka Crisis Philip D. Cloutier (1949–1998), American politician Réal Cloutier (born 1956), Canadian ice hockey player Réjean Cloutier (born 1960), Canadian ice hockey player Roger Cloutier (born 1965), American military general Roland Cloutier (born 1957), Canadian ice hockey player Sheila Watt-Cloutier (born 1953), Canadian Inuit activist Suzanne Cloutier (1927–2003), Canadian film actress Suzanne Cloutier (gymnast) (born 1947), Canadian gymnast Sylvain Cloutier (born 1974), Canadian ice hockey player Sylvie Cloutier, Canadian geneticist and academic T. J. Cloutier (born 1939), American professional poker player Véronique Cloutier (born 1974), Canadian TV and radio personality William Cloutier, Canadian singer Zacharie Cloutier (c. 1590–1677), French carpenter and one of the founders of Beauport, Quebec