Mangiagalli is an Italian surname literally translating to 'rooster-eater'. Notable people with the surname include:
Luigi Mangiagalli (1850–1928) was an Italian scientist, philanthropist, politician Mangiagalli Clinic, a ward of the Milan Polyclinic named after Luigi Mangiagalli Riccardo Pick-Mangiagalli (1882–1949), Italian composer and pianist