Lotts Creek may refer to the following streams in the United States:
Lotts Creek (East Fork Grand River tributary) in Iowa and Missouri Lotts Creek (Kentucky) in Kentucky
Lotts Creek may refer to the following townships in the United States:
Lotts Creek Township, Kossuth County, Iowa, Kossuth County, Iowa Lotts Creek Township, Ringgold County, Iowa, Ringgold County, Iowa
See also Lotts (disambiguation)