Khawam is a surname. Notable people with the name include:

Georges Khawam (born 1959), Syrian Melkite Catholic hierarch Gigi Khawam Kelley, Lebanese-American philanthropist, activist, and diplomatic advisor Joseph Khawam, BA (born 1968), Syrian-born Melkite Catholic hierarch, Apostolic Exarch of Venezuela René R. Khawam (1917–2004), Syrian translator known for translating the Qur'an, One Thousand and One Nights, etc. Roger Khawam (born 1993), Egyptian artist, record producer, beatmaker, songwriter and rapper Rony Khawam (born 1964), Lebanese judoka Sélim Khawam, dealer in Egyptian antiquities, founder of the firm that became Khawam Brothers