Wissel is a surname of German origin. Notable people with the surname include:
Adolf Wissel (1894–1973), German genre painter Christian Wissel, German physicist Derek von Wissel, politician and businessman from Swaziland Hal Wissel (1939–2025), American basketball coach Max Wissel (born 1989), German former racing driver Rudolf Wissell (1869–1962), German politician
See also Diederik Wissels (born 1960), Dutch jazz pianist Pearl van der Wissel (born 1984), Dutch handballer Frederick von Wissell (died 1820), British Army officer during the Napoleonic Wars Rudolf Wissell (1869–1962), German politician, a member of the Reichstag during the Weimar Republic