Tshegofatso/Tshehofatso is a Sotho-Tswana name meaning "blessing." Notable people with the name include:

Tshego (born 1990), South African-American singer-songwriter Tshehofatso Meagan Chauke (born 1992), South African politician Tshego Gaelae, South African beauty queen, Mrs. World 2025 Tshegofatso Mabaso (born 1996), South African soccer player Tshogofatso Motlogelwa (born 2000), South African soccer player