Makhloufi () is an Arabic surname, commonly used in Algeria. Notable people with the surname include:
Abdelkader Ould Makhloufi (1944–2025), Algerian boxer Amar Makhloufi (born 1943), Algerian engineer and politician Mehdi Makhloufi (born 1978), French-Algerian footballer Rabia Makhloufi (born 1986), Algerian steeplechase runner Taoufik Makhloufi (born 1988), Algerian middle-distance runner
See also Makhlouf