Mirchandani is a surname of Indian origin, commonly used by Sindhi Hindus. Notable people with the surname include:
Kamna Mirchandani (born 1979), Indian-born Canadian cricketer Lidia Mirchandani (born 1976), Spanish basketball player Nanikram Dharamdas Mirchandani (1890–1946), Sindhi novelist, essayist, and actor-dramatist Rajesh Mirchandani, British communications executive and former television journalist of Indian Sindhi descent Rohan Mirchandani (1981 or 1982–2024), Indian businessman and entrepreneur Sanjay Mirchandani, President & Chief Executive Officer of Commvault