The 2024–25 Cal Poly Mustangs women's basketball team represented California Polytechnic State University, San Luis Obispo during the 2024–25 NCAA Division I women's basketball season. The Mustangs, led by third-year head coach Shanele Stires, played their home games at the Mott Athletics Center in San Luis Obispo, California as a member of the Big West Conference.

The Mustangs finished the season 14–8, 8–12 in Big West play, to finish in eighth place. In the Big West tournament, they defeated UC Santa Barbara in the first round before losing to UC San Diego in the quarterfinals.

Previous season The Mustangs finished the 2023–24 season 17–14, 13–7 in Big West play, to finish in a three-way tie for third place. They were defeated by UC Davis in the quarterfinals of the Big West tournament. They received an at-large bid to the WNIT, where they fell to Pacific in the first round.

Roster

Schedule and results

!colspan=12 style=""| Exhibition

!colspan=12 style=""| Regular season

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Sources:

References