Madarame () is a Japanese surname. Notable people with the surname include:
Hideo Madarame (born 1944), Japanese former cyclist Makio Madarame (born 1972), Japanese former cyclist
Fictional characters Baku Madarame, the main character from Usogui Ichiryusai Madarame, a major antagonist from Persona 5 Shion Madarame, an antagonist from Tokyo Revengers