Juan Cárdenas may refer to:
(1563–1609), Spanish physician and scientist who worked in New Spain Juan Cárdenas (Jesuit) (1613–1684), Spanish theologian and author Juan Francisco de Cárdenas (1881–1966), Spanish diplomat Juan Cárdenas Arroyo (1939–2024), Colombian painter (born 1949), Ecuadorian politician, governor of Cañar Juan Cárdenas (writer) (born 1978), Colombian writer and translator