Palomeque is a surname. Notable people with the surname include:
Cristian Palomeque (born 1994), Colombian footballer Diego Palomeque (born 1993), Colombian sprinter Ezequiel Palomeque (born 1992), Colombian footballer Fernando Palomeque (born 1968), Mexican football player and manager Flor María Palomeque (born 1979), Ecuadorian actress, dancer, and model Karen Palomeque (born 1994), Colombian Paralympic athlete Lincoln Palomeque, Colombian actor Manuel Palomeque (born 1967), Spanish footballer Mathías Palomeque (born 1986), Uruguayan rugby player Rubén Palomeque (born 1980), Spanish steeplechase runner Rubén Palomeque (footballer) (born 1994), Spanish footballer