Esau is the older son of Isaac in the Hebrew Bible.

Esau may also refer to:

Cyclone Esau, Category 4 South Pacific and Australian region cyclone in 1992 Esau (film), 2019 drama film Esau (name), Hebrew given name and surname

Species Arixenia esau, species of earwig Eocarterus esau, species of ground beetle Eurysops esau, species of beetle Mirapinna esau, species of fish