Topliff may refer to:
People Given name Topliff Olin Paine (1893-1922), American airmail and Army Air Corps pilot
Surname Alfred Topliff (1799-1879), American teacher, surveyor, and politician E. Curtis Topliff (1829/30–1895), American businessman and politician Susan Topliff Davis (1862-1931), American civic and religious leader
Other Nathaniel Topliff Allen Homestead, historic house in West Newton, in Newton, Massachusetts, U.S.