Mondello is an Italian toponymic surname of Mondello, Italy. Notable people with the surname include:
Bob Mondello (born 1949), American film critic Ferdinand J. Mondello (1906–1992), American politician Joseph Mondello (1938–2022), American politician Lisette M. Mondello, American government official Massimiliano Mondello (born 1975), American table tennis player Romina Mondello (born 1942), Italian actress and television personality Toots Mondello (1911–1992), American saxophonist
Fictional characters
Larry Mondello, character from Leave It to Beaver