Osama Mahmoud Abdel Khalek Mahmoud (born 27 January 1966) is an Egyptian diplomat who has served as the Permanent Observer of the League of Arab States to the United Nations since 2026. He previously served as the Permanent Representative of Egypt to the United Nations from 2021 to 2025, and as Permanent Representative to the African Union in 2018 and the Economic Commission for Africa (ECA) in 2021.

Biography Mahmoud was born on 27 January 1966. He obtained a bachelor's degree in engineering from Cairo University in 1988.

In July 2016, he assumed the role of deputy minister for Foreign Affairs, focusing on African affairs until October 2018. Prior to this appointment, he served as the deputy permanent representative to the United Nations in New York from July 2011 to July 2016. He began his career in the Ministry for Foreign Affairs as a counselor in the Nazif Cabinet, 2009.

Mahmoud served as the Deputy Permanent Representative to the African Union in Addis Ababa, Ethiopia, from 2005 to 2009. Prior to that, he was the third secretary at the Permanent Mission to the League of Arab States from 1998 to 2000.

On 16 September 2021, he presented his credentials to Secretary-General António Guterres as Permanent Representative of Egypt to the United Nations. During his tenure he chaired the Fifth Committee of the General Assembly at its seventy-eighth session. He was succeeded by Ihab Mostafa Awad Mostafa in December 2025.

In 2026, Mahmoud was appointed Permanent Observer of the League of Arab States to the United Nations in New York, succeeding Maged Abdelfattah Abdelaziz.

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