John Symes may refer to:
John Symes (cricketer) (1879–1944), English cricketer John Symes (politician, born 1573) (1573–1661), English politician and lawyer John Symes Berkeley (1663–1736), English Member of Parliament John Foster Symes (1878–1951), United States district judge
See also John Sims (disambiguation) John Simms (disambiguation)