Staykov (Bulgarian Стайков, feminine: Staykova) is a Bulgarian surname. Notable people with the surname include:
Georgi Staykov (born 1964), Bulgarian actor Ivan Staykov (1926–2003), Bulgarian cross-country skier Nencho Staykov (born 1955), Bulgarian cyclist Nikola Staykov (1907–1974), Bulgarian footballer Sara Staykova (born 1993), Bulgarian rhythmic gymnast Stefan Staykov (born 1949), Bulgarian footballer