Osgood House may refer to the following American houses:

Dr. H. G. Osgood House, Gosport, Indiana, on the National Register of Historic Places (NRHP) Nathaniel Osgood House, Durham, Maine, on the NRHP Osgood Family House, Fryeburg, Maine, on the NRHP Unitarian Universalist Church of Medford and the Osgood House, Medford, Massachusetts, a Unitarian Universalist church building and parsonage house on the NRHP Col. John Osgood House, North Andover, Massachusetts, on the NRHP Samuel Osgood House (North Andover, Massachusetts), on the NRHP Samuel Osgood House, Manhattan, New York, first official residence of the President of the United States

See also Nathaniel Bowditch House, Sale, Massachusetts, sometimes called the Bowditch-Osgood House, on the NRHP