Marie-Luce is a French feminine compound given name. It may refer to:
Marie-Luce Brasier-Clain (born 1959), French politician Marie-Luce Penchard (born 1959), French politician Marie-Luce Romanens (born 1973), Swiss orienteer Marie-Luce Waldmeier (born 1960), French alpine skier
See also Marie-Lucie, another given name