Meshack is a masculine given name. Notable people with the name include:
Dumezweni Meshack Mthimkhulu, Motswana politician Meshack Abel Mwankina (born 1987), Tanzanian footballer Meshack Asare (born 1945), Ghanaian writer Meshack Franklin (1722–1839), American politician Meshack Kondwani, Zimbabwean boxer Meshack Lufile (born 1992), Canadian basketball player Meshack Maphangule (born 1991), South African footballer Meshack Mavuso (born 1977), South African actor Meshack Opulukwa (born 1967), Tanzanian politician Meshack Radebe (1948/1949–2021), South African politician Meshack Ratliff (1832–1922), American Army officer and politician Meshack Roberts, American slave, minister and politician