Kouame is both a given name and a surname. Notable people with the name include:
Kouame Aholou (born 1970), Togolese sprinter Kouame Autonne (born 2000), Ivorian-Emirati footballer Kouamé Botué (born 2002), Ivorian footballer Kouamé Lougué, Burkinabé politician Kouame N'Douba (born 1964), Ivorian sprint canoer Kouamé Ouattara (born 1991), Ivorian footballer Adjoua Flore Kouamé (born 1964), Ivorian novelist Akissi Kouamé (1955–2022), Ivorian army officer Alexander Kouame (born 1988), Ivorian footballer Ange Kouamé (born 1996), Ivorian footballer Ange Kouame (born 1997), Ivorian-Filipino basketball player Axel Kouame (born 2003), Ivorian footballer Basile Aka Kouamé (born 1963), Ivorian footballer Bruno Kouamé (1927–2021), Ivorian bishop Christian Kouamé (born 1997), Ivorian footballer Djems Kouamé (born 1989), Canadian football player Eugène Koffi Kouamé (1988–2017), Ivorian footballer Koffi Kouamé (born 1995), Ivorian footballer Koli Kouame, Ivorian United Nations official Rominigue Kouamé (born 1996), Ivorian footballer Taky Marie-Divine Kouamé, French cyclist Valentin Kouamé, Burkinabé footballer Kouassi Kouamé Patrice (born 1962), Ivorian politician